The North Carolina Highway Patrol said a wreck shut down NC Highway 99 along the Belhaven bridge in Beaufort County.
According to troopers, the wreck happened Tuesday around 7 p.m.
A truck crossed the center line and hit a SUV head on. Both drivers of the vehicles were taken to a hospital.
The driver of the truck was charged with crossing the center line and DWI, although officials said alcohol was not involved.
An investigation will determine what the truck driver had in his system, officials said.